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Kenji Watanabe Selected Research

colibactin

2/2023Screening method toward ClbP-specific inhibitors.
12/2022Advancing the Biosynthetic and Chemical Understanding of the Carcinogenic Risk Factor Colibactin and Its Producers.
3/2022Induction of DNA Damage in Mouse Colorectum by Administration of Colibactin-producing Escherichia coli, Isolated from a Patient With Colorectal Cancer.
1/2022Association of Escherichia coli containing polyketide synthase in the gut microbiota with colorectal neoplasia in Japan.
1/2021Isolation of New Colibactin Metabolites from Wild-Type Escherichia coli and In Situ Trapping of a Mature Colibactin Derivative.
1/2021Mother-to-infant transmission of the carcinogenic colibactin-producing bacteria.
11/2020Characterization of Colibactin-Producing Escherichia coli Isolated from Japanese Patients with Colorectal Cancer.
1/2019Activity-Based Probe for Screening of High-Colibactin Producers from Clinical Samples.
1/2019In vitro genotoxicity analyses of colibactin-producing E. coli isolated from a Japanese colorectal cancer patient.

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Kenji Watanabe Research Topics

Disease

43Ulcerative Colitis
04/2024 - 05/2003
38Crohn Disease (Crohn's Disease)
03/2024 - 09/2003
35Neoplasms (Cancer)
01/2024 - 12/2003
16Carcinogenesis
01/2023 - 01/2004
16Infections
01/2021 - 05/2009
14Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2021 - 09/2003
13Inflammation (Inflammations)
02/2024 - 09/2007
13Pathologic Constriction (Stenosis)
10/2023 - 06/2001
12Colorectal Neoplasms (Colorectal Cancer)
02/2023 - 10/2012
12Hemorrhage
01/2022 - 03/2007
7Necrosis
02/2024 - 03/2014
7Atrophy
06/2022 - 01/2013
6Gastroesophageal Reflux (GERD)
01/2015 - 01/2010
5Carcinoma (Carcinomatosis)
05/2024 - 01/2006
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2023 - 11/2021
5Wounds and Injuries (Trauma)
01/2023 - 07/2012
5Stomach Neoplasms (Stomach Cancer)
04/2020 - 02/2010
5Stomach Ulcer (Gastric Ulcer)
05/2013 - 11/2008
4COVID-19
12/2024 - 07/2023
4Abdominal Pain (Pain, Abdominal)
03/2024 - 01/2011
4Lung Neoplasms (Lung Cancer)
01/2024 - 05/2003
4Hypersensitivity (Allergy)
08/2022 - 01/2019
4VLCAD deficiency
02/2021 - 06/2018
4Liddle Syndrome
01/2021 - 06/2014
4Esophageal Neoplasms (Esophageal Cancer)
12/2020 - 04/2016
4Neoplasm Metastasis (Metastasis)
04/2020 - 01/2012
4Pain (Aches)
04/2019 - 06/2001
4Breast Neoplasms (Breast Cancer)
10/2018 - 03/2005
4Osteoporosis
10/2017 - 03/2008
4Rheumatoid Arthritis
01/2017 - 01/2008
4Ulcer
11/2015 - 01/2010
4Heartburn (Pyrosis)
03/2015 - 06/2010
3Adenocarcinoma of Lung
05/2024 - 11/2021
3Dysmenorrhea (Menstrual Pain)
12/2023 - 01/2015
3Fistula
04/2023 - 06/2008
3Mitochondrial Diseases (Mitochondrial Disease)
11/2022 - 03/2011
3Body Weight (Weight, Body)
06/2022 - 08/2003
3Common Cold
01/2022 - 05/2013
3Disease Progression
11/2021 - 05/2005
3Rhabdomyolysis
02/2021 - 06/2014
3Fatigue
02/2021 - 11/2004
3Osteoarthritis
03/2019 - 06/2015
3Hepatocellular Carcinoma (Hepatoma)
12/2017 - 08/2011

Drug/Important Bio-Agent (IBA)

14Messenger RNA (mRNA)IBA
01/2021 - 02/2002
13Proteins (Proteins, Gene)FDA Link
05/2024 - 03/2005
11Capsules (Microcapsules)IBA
10/2023 - 01/2006
9colibactinIBA
02/2023 - 01/2019
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2023 - 08/2007
9AcidsIBA
07/2022 - 07/2009
9EnzymesIBA
09/2019 - 09/2003
8Adalimumab (Humira)FDA Link
01/2021 - 09/2014
8Infliximab (Remicade)FDA Link
01/2021 - 03/2014
7Biomarkers (Surrogate Marker)IBA
01/2023 - 10/2012
7Peptides (Polypeptides)IBA
08/2022 - 09/2004
7Proton Pump InhibitorsIBA
03/2015 - 11/2008
6Immunologic Factors (Immunomodulators)IBA
11/2023 - 03/2014
6SteroidsIBA
10/2023 - 05/2003
6vedolizumabIBA
01/2022 - 01/2019
6Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
03/2014 - 03/2007
6AntigensIBA
10/2012 - 06/2002
5CytokinesIBA
02/2024 - 07/2009
5C-Reactive ProteinIBA
10/2023 - 04/2014
5Monoclonal AntibodiesIBA
07/2021 - 08/2010
5Fatty Acids (Saturated Fatty Acids)IBA
02/2021 - 06/2018
4keishibukuryoganIBA
12/2023 - 03/2005
42-mercaptopurineIBA
11/2023 - 09/2019
4Anti-Bacterial Agents (Antibiotics)IBA
02/2023 - 12/2003
4MutagensIBA
02/2023 - 01/2020
4AntibodiesIBA
01/2023 - 09/2003
4PolyketidesIBA
01/2022 - 07/2009
4Mesalamine (Mesalazine)FDA LinkGeneric
01/2022 - 09/2003
4InterleukinsIBA
01/2020 - 07/2009
4Adrenal Cortex Hormones (Corticosteroids)IBA
11/2019 - 01/2008
4Budesonide (Pulmicort)FDA LinkGeneric
01/2019 - 07/2016
4bu-zhong-yi-qi-tangIBA
01/2017 - 06/2002
4CollagenIBA
01/2014 - 03/2013
3RNA (Ribonucleic Acid)IBA
05/2024 - 01/2023
3toki-shakuyaku-sanIBA
12/2023 - 01/2015
3Antimicrobial PeptidesIBA
07/2023 - 01/2013
3BilirubinIBA
04/2023 - 05/2019
3Reactive Oxygen Species (Oxygen Radicals)IBA
11/2022 - 01/2006
3Leukocyte L1 Antigen Complex (Calgranulin)IBA
07/2022 - 10/2018
3Carcinoembryonic AntigenIBA
01/2022 - 10/2012
3AminesIBA
01/2022 - 01/2020
3Ustekinumab (CNTO 1275)FDA Link
07/2021 - 01/2020
3BezafibrateIBA
02/2021 - 06/2018
3Glycyrrhizic Acid (Glycyrrhizin)IBA
01/2021 - 05/2019
3DNA (Deoxyribonucleic Acid)IBA
12/2020 - 01/2002
3Azathioprine (Imuran)FDA LinkGeneric
09/2019 - 11/2016
3Long-Chain Acyl-CoA Dehydrogenase (Long-Chain-Acyl-Coenzyme A Dehydrogenase)IBA
09/2019 - 06/2018
3Carrier Proteins (Binding Protein)IBA
05/2019 - 03/2012

Therapy/Procedure

39Therapeutics
05/2024 - 05/2003
13Kampo Medicine (Kampo)
12/2023 - 10/2005
6Drug Therapy (Chemotherapy)
02/2023 - 03/2013
6Blood Component Removal (Apheresis)
04/2020 - 12/2009
4Transplantation
01/2023 - 06/2006
4Aftercare (After-Treatment)
06/2022 - 01/2010
4Hepatectomy
01/2021 - 08/2011
4Colectomy
07/2020 - 01/2011
3Gastrectomy
10/2021 - 01/2016